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Mayo Clinic Explains How Chronic Pain 
Persists, Even Without Injury

Science & Research

One of the most confusing aspects of chronic back pain is this:“If the injury is gone… why does the pain remain?” Many people struggle for years with back pain that makes no mechanical sense. Scans show nothing new. Treatments fail. The body should be healed
—but the pain continues.

The Mayo Clinic has a name for this phenomenon:Central sensitization. And it may be the single most important (and overlooked) 
reason why your back still hurts.


What Is Central Sensitization?

According to The Mayo Clinic Guide to Pain Relief, central sensitization happens when the nervous system becomes overly reactive to pain signals—even long after the original injury has healed. Think of it like a car alarm stuck in the “on” position. Or a radio dial jammed on full volume. Your system starts overinterpreting normal or harmless signals as threats. “The brain and spinal cord can create symptoms by themselves,” Mayo researchers explain. “Even in the absence of new damage.”

It’s All About Neuroplasticity

Neuroplasticity means your brain can rewire itself in response to experience. That’s good news when you’re learning a skill. But not when your nervous system is learning to expect pain.

Here’s how the Mayo Clinic puts it:“As the brain becomes faster at processing pain signals, it can no longer accurately determine which inputs indicate danger. It begins to amplify pain even in response to minor or non-harmful sensations.”

This creates a vicious cycle:

  • You hurt
  • You fear the pain
  • Your nervous system listens—and turns up the dial again

Real-World Examples

Central sensitization explains a host of strange pain patterns:

  • Pain that flares after stress, not movement
  • Pain that persists long after tissues have healed
  • Phantom limb pain (where the limb is gone, but the pain remains)
  • Sensitivity to light touch, sitting, or gentle movement
  • Pain that bounces from place to place

It’s not “in your head,” it’s in your nervous system. And the good news is it can be reversed.

What /the Makepeace Method Adds

If your pain isn’t coming from tissue damage anymore, then the solution can’t be physical treatment alone. The Makepeace Method helps you recognize these patterns—and calm the alarm system that’s been stuck in the on position.

You don’t need to keep chasing structural solutions. You need to retrain your brain.

Sources:

https://connect.mayoclinic.org/blog/chronic-pain-symptoms-rehabilitation/newsfeed-post/hello/

https://mcpress.mayoclinic.org/living-well/what-is-central-sensitization-and-how-does-it-relate-to-pain/

You don’t have to live with this pain.

The Makepeace Method is a guided 7-day program that helps you calm your nervous system, retrain your brain’s pain signals, and finally feel safe in your own body again.

Start the Method - $97

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What You Get Inside The Makepeace Method

Most people arrive at The Makepeace Method after months or years of chasing physical fixes — stretches, adjustments, injections, mattresses, supplements, MRIs. They’ve tried everything except the one thing that actually changes chronic pain: Understanding what the pain is.

How Robert Beat His Back Pain After a Lifetime of Pressure

Robert’s pain arrived after decades of pushing himself at work. His scans showed degeneration, but so do most for people his age. When he finally slowed down and addressed the stress behind his drive, the pain eased—not through treatment, but through understanding.

The Painkiller That Killed the Truth

In 1996, Purdue Pharma introduced a drug it described as a breakthrough in pain management. OxyContin was marketed as modern, safe, and compassionate—a scientific solution to human suffering. What followed is now one of the worst public health disasters in history. More than a quarter million people in North America have died from prescription opioid overdoses.

Real people. Real relief.

These are real stories from people who were stuck in pain—until they tried the Makepeace Method. Now they're free.

One day, you bend down to pick up a sock—and your back goes out.

Name, 32
Problem

“Knowing what I know now, I regret having back surgery.”

Dr. Ken H., 72
Back & leg pain

“I feel so much better — and I’m grateful this exists.”

Rupi V., 35
Back pain

“This took my pain from a 9 or 10 down to a 1 or 2.”

Tim B., 52
Butt & back pain

“After doing the program, I got up from my desk one day and the pain and tingling were just gone.”

Joe B., 40
Neck pain

“I've had significant improvements in my pain levels. I now feel confident about managing my back health.”

Justin S., 55
Back pain

“This method makes a complex idea easy to implement. Bottom line: I’m feeling much better.”

Terry G., 69
Back & leg pain

“I was bedridden for weeks. Now the pain is gone, and when it flares, I can shut it off.”

Ian C., 48
Neck pain

“I was a massage therapist for 30 years. Several weeks ago I started an excruciating ordeal with back pain. The Makepeace Method was life changing for me. My back has improved tremendously. Thank you a million times over.”

Colleen K., 61
Neck pain

“I loved your course. It was a blessing listening to your videos. It has given me hope on my healing journey.”

Luis D., 48
Back and Leg Pain

“I had been truly suffering for months. Within a few days, I was moving freely again. Thank you.”

Ruth G., 62
Back Pain
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You've done your time in pain. Now take your life back.

You’ve fought hard and tried it all, but the burden was never yours to carry forever. Your brain is ready to reset, your body to feel safe again. Pain is not who you are - it’s time to reclaim your life.