
What if chronic back pain isn’t just a medical condition… but a false alarm in the brain?
That’s the radical—and now scientifically validated—premise behind a groundbreaking study published in JAMA Psychiatry by researchers at the University of Colorado.
And the results were jaw-dropping:
Two-thirds of participants became pain-free or nearly pain-free. No medication. No surgery. Just a shift in how they understood their pain.
Led by neuroscientist Yoni Ashar, the study followed 151 people who had suffered from chronic back pain for at least six months.
They were randomly assigned to one of three groups:
After four weeks:
The intervention focused on teaching patients that pain isn’t always a sign of damage—especially once healing has already occurred.
Participants learned to:
“The brain can generate pain even in the absence of injury,” said lead author Yoni Ashar.
“And people can unlearn that pain.”

Before and after treatment, participants underwent brain scans.
The results showed reduced activity in key pain-processing regions, including the anterior insula and midcingulate cortex—suggesting the brain was no longer amplifying the pain signal.
This wasn’t just a mindset shift. It was a neural shift.
A global survey estimated that 90% of chronic back pain cases have no identifiable structural cause. But that doesn’t mean the pain isn’t real.
It means the brain has good reason to be sounding the alarm—often based on unresolved emotional tension, fear, or learned pain associations.
And just as the brain can learn pain… it can unlearn it.
This study validates what pioneers like Dr. John Sarno knew decades ago: Chronic pain is often the brain’s way of protecting you—from thoughts and emotions it deems too dangerous to feel.
At Makepeace, we don’t just treat pain as a signal to manage.
We help you explore why the signal is there in the first place.
You don’t need endless exercises or cognitive drills.
You need a new lens on what the pain is trying to say.
Sources:
https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2784694
Most people arrive at The Makepeace Method after months or years of chasing physical fixes — stretches, adjustments, injections, mattresses, supplements, MRIs. They’ve tried everything except the one thing that actually changes chronic pain: Understanding what the pain is.

Robert’s pain arrived after decades of pushing himself at work. His scans showed degeneration, but so do most for people his age. When he finally slowed down and addressed the stress behind his drive, the pain eased—not through treatment, but through understanding.

In 1996, Purdue Pharma introduced a drug it described as a breakthrough in pain management. OxyContin was marketed as modern, safe, and compassionate—a scientific solution to human suffering. What followed is now one of the worst public health disasters in history. More than a quarter million people in North America have died from prescription opioid overdoses.
You’ve fought hard and tried it all, but the burden was never yours to carry forever. Your brain is ready to reset, your body to feel safe again. Pain is not who you are - it’s time to reclaim your life.